CryoSPARC Discuss

Topic		Replies	Views	Activity
CryoSPARC v5.0.0-v5.0.7: Fix for Live session compaction bug Troubleshooting Hi all, We would like to inform users that we have discovered an issue in CryoSPARC v5.0.0-v5.0.7 where, due to a rare race condition scenario, initiating CryoSPARC Live session compaction may incorrectly delete files o…		1	64	November 5, 2026
Before You Post: Troubleshooting Guidelines Troubleshooting Dear cryoSPARC users, Thank you for communicating with us on the discussion forum. Before you post your topic, check the following items: Are you on the latest version of cryoSPARC? cryosparcm update and see Softwar…		0	13001	October 15, 2018
Encountered a Closed Topic? Troubleshooting Forum moderators may Close topics for various reasons. If you find that a topic to which you would like to add a post has been Closed, please Create a new topic for your post. In your post, include the URL of the topic…		0	1961	November 30, 2023
Strategies to improve ligand occupancy and local density in a heterotetrameric protein with potentially heterogeneous ligand binding Cryo-EM Data Processing		0	18	November 13, 2026
Backing up a ~1.2 TB v5 database: can we rely on `recover` plus instance config exports, and is the size expected? Install, Configure and Update		2	49	November 12, 2026
V5.0.7 project stuck in failed import state after historical DB-loss recovery Data Management		3	88	November 12, 2026
SIGSEGV in core/ioengine/core.so across multiple job types Troubleshooting		6	164	November 12, 2026
Denoiser training during live processing CryoSPARC Live feature_request		1	39	November 12, 2026
Add fp16 output option for particle subtraction Utilities feature_request		3	369	November 12, 2026
Feature Request - Output grouped particles from Orientation Diagnostics Features and Functionality feature_request		3	74	November 12, 2026
Odd Dip in FSC Curve in 3D Flex 3D Flexible Refinement		3	119	November 12, 2026
5.0.7 Cryosparc live: Stuck in Restoration Failed CryoSPARC Live		10	151	November 12, 2026
SIGSEGV error during reference based motion correction, just after refmotion_hyperparameters Troubleshooting	$doesnotdiffract - Original Poster, Most Recent Poster$	8	108	November 12, 2026
Cryosparc offline cluster jobs Install, Configure and Update		1	53	November 11, 2026
Fix for v5.1+ on DGX Spark worker node Troubleshooting		1	45	November 11, 2026
Cannot download benchmark data via web browser Troubleshooting		3	28	November 11, 2026
Moving the whole database and data to a new cluster Data Management		15	190	November 11, 2026
Cache particles ==>3D classification cache false Application		3	84	November 10, 2026
Optional spatial prior for local CTF refinement? CTF Refinement feature_request		1	91	November 10, 2026
Pixi error when updating 5.0.7 to 5.1.2 Install, Configure and Update		4	59	November 10, 2026
V5.1.1 local-res in volume viewer Application		1	57	November 10, 2026
Tree view for projects with 3D Flex jobs Application		3	50	November 10, 2026
CryoSPARC 5.1: specifications of system(s) used for performance improvements Hardware and Performance		2	111	November 10, 2026
Some input parameters ignored in Manually Curate Exposure (v5.1.1) Exposure Curation		1	56	November 9, 2026
V5.1.0 volume viewer not working Application		17	326	November 9, 2026
Cryosparc v5.1.1 live continous import not working CryoSPARC Live		3	98	November 9, 2026
Topaz training fails with exposures exported from Cryosparc Live Particle Picking		1	29	November 9, 2026
Suggestions forSeparating Conformational Heterogeneity in cryoSPARC Cryo-EM Data Processing		3	89	November 7, 2026
Failed to upgrade to 5.1.0 - supervisorctl error Install, Configure and Update		9	199	November 7, 2026
Patch CTF with Junk Mask fails when F-crop 3/4 is applied in Patch Motion in v5.1.0 Troubleshooting		1	65	November 6, 2026

CryoSPARC v5.0.0-v5.0.7: Fix for Live session compaction bug

Hi all, We would like to inform users that we have discovered an issue in CryoSPARC v5.0.0-v5.0.7 where, due to a rare race condition scenario, initiating CryoSPARC Live session compaction may incorrectly delete files o…

1

64

November 5, 2026

Before You Post: Troubleshooting Guidelines

Troubleshooting

Dear cryoSPARC users, Thank you for communicating with us on the discussion forum. Before you post your topic, check the following items: Are you on the latest version of cryoSPARC? cryosparcm update and see Softwar…

0

13001

October 15, 2018

Encountered a Closed Topic?

Troubleshooting

Forum moderators may Close topics for various reasons. If you find that a topic to which you would like to add a post has been Closed, please Create a new topic for your post. In your post, include the URL of the topic…