| Topic | Replies | Views | Activity | |
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Updates to 3D Refinement and Cryo-EM Foundations Guide pages
Hello CryoSPARC users! We have just released several new and updated guide pages! A brief summary of the additions and changes follows. We hope that the guide serves as a useful resource for all members of the cryo-EM co… |
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1 | 14 | July 13, 2026 |
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Registration is open for the CryoSPARC Workshop (September 2026)
Registration is now open for the upcoming two-day CryoSPARC Workshop being held in Toronto in September 2026. As part of the Canadian Cryo-EM Nexus, The Hospital for Sick Children (SickKids) and Structura Biotechnology … |
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1 | 117 | July 6, 2026 |
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Before You Post: Troubleshooting Guidelines
Dear cryoSPARC users, Thank you for communicating with us on the discussion forum. Before you post your topic, check the following items: Are you on the latest version of cryoSPARC? cryosparcm update and see Softwar… |
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0 | 12780 | October 15, 2018 |
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Encountered a Closed Topic?
Forum moderators may Close topics for various reasons. If you find that a topic to which you would like to add a post has been Closed, please Create a new topic for your post. In your post, include the URL of the topic… |
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0 | 1907 | November 30, 2023 |
| EMDB FSC files in XML format |
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7 | 2096 | July 13, 2026 |
| Project import fail v5.0.6 |
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1 | 23 | July 13, 2026 |
| Issues in running Denoise Micrograph job |
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3 | 48 | July 13, 2026 |
| Jobs exported on 5.0.4 do not import correctly on 4.7.1 |
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11 | 95 | July 13, 2026 |
| Micrograph Junk Detector: IndexError |
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6 | 171 | July 13, 2026 |
| Create a report from a session? |
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8 | 803 | July 13, 2026 |
| Particle alignments |
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1 | 10 | July 13, 2026 |
| Local Refinement Stuck After Unbinning |
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3 | 10 | July 13, 2026 |
| Filament Picking option in Manual Picker |
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4 | 84 | July 13, 2026 |
| CryoSPARC5 can only recognize 6 of 8 GPUs |
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3 | 39 | July 13, 2026 |
| Sample gets aggregated on the grid |
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12 | 97 | July 13, 2026 |
| 5.0.6: ab-initio reconstruction loop |
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15 | 196 | July 13, 2026 |
| I met the problem in NU refinement |
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1 | 19 | July 13, 2026 |
| CryoSPARC Update for Ubuntu 26.04 LTS? |
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4 | 63 | July 13, 2026 |
| Refinement bottleneck for a 12-TM membrane protein in DDM |
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1 | 26 | July 13, 2026 |
| Simplifying import jobs? |
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4 | 586 | July 13, 2026 |
| Add per-user file system limitations that can be managed at an instance level? |
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1 | 49 | July 13, 2026 |
| Good 2D classes but bad ab-initio reconstruction |
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9 | 616 | July 13, 2026 |
| Minimize/background upload interface? |
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1 | 45 | July 13, 2026 |
| Viewing distribution lookup table / dynamic viewer |
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1 | 58 | July 13, 2026 |
| [Feature request] 3D Classification quick action: Build Local Refinement (Each Class) |
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2 | 52 | July 13, 2026 |
| 5.0.6: 2d classification crash |
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2 | 38 | July 10, 2026 |
| CryoSPARC 3D Classification ~50× slower on cluster than workstation. Disabling SSD cache improves performance |
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1 | 52 | July 9, 2026 |
| Upgraded to v5.0.6: No route to host |
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9 | 105 | July 9, 2026 |
| RBMC multi-map GUI bug |
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3 | 54 | July 9, 2026 |
| Almost regular occurence of "database EXITED" |
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27 | 1214 | July 9, 2026 |