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Losing ~30% of particles between 3D Classification and downstream jobs (Extraction/Reconstruction/Local Refine) — combined particle count doesn't match
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3
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103
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September 15, 2026
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Topaz overwhelmed by mic input?
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1
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88
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September 15, 2026
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Bug in cloning session + template picker?
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1
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57
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September 14, 2026
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Reference-based motion correction: "operands could not be broadcast together"
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4
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108
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September 14, 2026
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CTF estimation/CTFfind4 error
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3
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93
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September 14, 2026
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ZFS pool strategy for CryoSPARC
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2
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126
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September 14, 2026
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Using 3D Flex to refine a small, unrestricted domain
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6
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663
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September 13, 2026
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How Can I reduce micelle-dominated alignment when applying HR-HAIR to a small GPCR?
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6
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257
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September 11, 2026
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Balance half sets
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7
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164
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September 11, 2026
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FSC-work/FSC-free gap, and curves not converging near FSC=0.143
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0
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64
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September 9, 2026
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Resolving smeary density for a protein complex dataset
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0
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94
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September 9, 2026
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Problem with topaz pick- test average precision is 0.1- picking false positives?
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0
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54
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September 9, 2026
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5.0.6: ab-initio reconstruction loop
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33
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595
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September 7, 2026
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CryoSPARC-5.0.6 vs CryoSPARC 4.6.2 resolution changes for non uniform refinement
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2
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132
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September 4, 2026
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SIGSEGV in core/ioengine/core.so across multiple job types
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5
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109
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September 4, 2026
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Extraction box parameter in RBMC
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0
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59
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September 4, 2026
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Reference model based ab-initio reconstruction
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8
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4510
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September 3, 2026
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Changing interval for retrying saving results to disk post-5.0.7
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3
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50
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September 2, 2026
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Inspect Picks job custom polygon request
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1
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60
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September 2, 2026
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The resolution of the big protein is low
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2
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132
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September 2, 2026
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V5.0.7 – Instance Testing / Benchmark job fails with AttributeError: 'str' object has no attribute 'stat' when benchmark data is missing
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4
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56
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September 1, 2026
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Heterogeneous reconstruction of small protein
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16
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505
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September 1, 2026
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RTX PRO 4000 Blackwell Xid 8 / CUDA_ERROR_LAUNCH_TIMEOUT in 2D Classification and Ab-initio
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9
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195
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September 1, 2026
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How to process highly flexible 150 kDa protein complex?
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6
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325
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September 1, 2026
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I/O error during Homogeneous Refinement after re-extracting unbinned particles
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1
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50
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August 31, 2026
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Reverting from symmetry expanded downsampled set to full scale and keep poses?
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0
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38
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August 31, 2026
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Tree view not loading
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3
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82
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August 31, 2026
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Anomalously low cFAR for interpretable map
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14
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1475
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August 30, 2026
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Best practice to split a project into two projects
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1
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94
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August 28, 2026
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CryoSPARC jobs fail after temporary network disconnection on a single workstation
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1
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60
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August 28, 2026
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