Picking/Curate Exposures Requests/Suggestions

Hi Cryosparc Team, would it be possible to have a merged curate exposures and manual picking job? When working with smaller sets of micrographs would be very helpful to be able to toss bad micrographs out once you have identified no potential manual picks. By the same reasoning it would be great to be able to place a high quality particle heavy micrographs in a separate group for specialized uses (later repicking, blob picker tuner, particle images for publication, etc). It can be frustrating to be in a curate exposures job and see the perfect micrograph for picking (yes, the UUID could be used I guess, but would be so tedious) but not be able to, vice versa it stinks when in a picking job and coming across a horrid micrograph that you have no clue how it survived preprocessing clean up but you can’t remove it because in active picking job.

Additionally it would be great if we could have multiple “containers” for our manual picks. Use case example is I am working with a particle which we suspect dimerizes, so in the dataset you see truncated monomer, true monomer, relaxed dimer (non-physiological), and some physiological dimer and each of these groups shows even more heterogeneity, it would be helpful to be able to sort my manual picks into separate groups, for several reasons (I do not yet want them classified)

Finally, it would be awesome in the inspect picks job could have some way to link the template used to pick to the particle. My thought being if I know I have very few “bottom” views, I can color code my “bottom” templates before picking (i.e assign the color blue to bottom) and after picking the inspect picks job will show all picks made using those templates as a blue dot in the ncc v. power graph. It would allow us the user to focus on particle curation on the views and angles we know need work a bit easier! I know I could have 3 picking jobs with templates separated by view but that gets messy/confusing to me at least, quickly.

Am new to Cryosparc and self teaching so if my requests don’t make much sense or there is a way to accomplish this don’t hesitate to let me know!

All the best and more,
John Hayden Hill

Thank you for the detailed feedback @jhh1492 , we really appreciate it! We’ve noted your suggestions and will work to support such cases in the future.

- Suhail

No thank yall for all the great work you put in to make the user experience as seamless as possible!

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