the parameters of Homogeneous Refinement and Non-uniform Refinement on Cryosparc v4.6 seems to be the same, so what are the differences? What are the differences between CTF optimization of Homogeneous Refinement/Non-uniform Refinement and the later independence Global CTF refinement/Local CTF refinement?
See the paper for an explanation of non-uniform refinement?
See also the guide, although ignore the estimates for GPU memory usage. NU refine (particularly the new codepath from 4.4 onwards) eats VRAM.