I have some dataset that ran reference based motioncor without an issue and some fails.
Successful run 1:
EER format, 129k particles -22800 movies, 600pix box binned to 300pix. default parameters
Successful run 2:
EER format, 554k particles - 3230 movies, 380pix box size. default parameters
Successful run 3:
F4i, Tiff format, 560k particles -2929 movies, 380pix box size, -Target number of particles 8000, 1 GPU, GPU threshold 40GB, in memory cache 240GB
Failed run:
EER format, 660k particles, 3463 movies, 380pix box, default parameters - job hangs randomly during hyperparameter tuning run 1.
F4i Tiff format (same set as successful run 3) 560k particles -2929 movies, 380pix box size, default parameters hang randomly during hyperparameter tuning run 1. When reducing particle number to 8000, it would run for a few iteration, than hang.