What is your pixel size, and are you binning (Fourier cropping) your particles? It appears you are limited by sampling, so if you unbin you may see better results.
Re the orientation distribution, there is clearly a degree of preferred orientation, but to judge whether it is significant just look at the map - do you see clear, interpretable density, or is it stretched/streaky?
It’s hard to tell from this snapshot, but I think yes it is stretched a bit - is that an alpha helix on the left? It looks like it is kind of smeared into the surrounding density, which would be consistent with the kind of artefacts seen with preferred orientation. To quantify, you can calculate a 3D-FSC.