cryoSPARC v. 2.13.2 standalone installation not start in web browser

I have fresh install “cryoSPARC v. 2.13.2 standalone” in CentOS 7.7 workstation today.
I don’t see any error during installation, but http://localhost:39000 doesn’t start.
Please help.Thansk.

Hi @wenhwai

Please ensure your firewall is not blocking ports 39000 to 39010. Try restarting cryoSPARC:

cryosparcm restart

If the issue persists, please share the output of:

cryosparcm status

(Do not include any personal info such as your license ID)


Hi Suhail,

Please look at below for the information of cryosparcm restart and cryosparcm status
There has been shown some Errors.
Thanks a lot.

[emma@xray1 ~]$ cryosparcm restart
CryoSPARC is running.
Stopping cryosparc.
unix:///tmp/cryosparc-supervisor-0a7a1b70e8cb83ee5e3d996ff3c14f1f.sock refused connection
ERROR: unix:///tmp/cryosparc-supervisor-0a7a1b70e8cb83ee5e3d996ff3c14f1f.sock refused connection (already shut down?)
Starting cryoSPARC System master process..
CryoSPARC is already running.
If you would like to restart, use cryosparcm restart

[emma@xray1 ~]$ cryosparcm status
CryoSPARC System master node installed at
Current cryoSPARC version: v2.13.2

cryosparcm process status:

unix:///tmp/cryosparc-supervisor-0a7a1b70e8cb83ee5e3d996ff3c14f1f.sock refused connection

Hi @wenhwai,

  1. Ensure cryoSPARC is turned off:
    cryosparcm stop
  2. Then, ensure no zombie processes are still running. Kill the processes if they are.
    ps -ax | grep “supervisord” (kill only the process that is running from your cryosparc2 install)
    ps -ax | grep “cryosparc2_command” (kill all the matching processes related to your cryosparc2 
    ps -ax | grep “mongod” (kill only the process running your cryosparc2 database)
    e.g. kill 82681
  3. Remove the socket file inside the /tmp folder
  4. Start cryoSPARC:
    cryosparcm start

Please let me know if this resolves the issue.


It is working.
Thanks a lot.