This particles comes from a Select 2D after running Cryosparc Live on a batch of tif files, which did not encounter any problems. Surprisingly, if I run the exact same job, but do not use the SSD for cache (which was used for the 2D classification), the job runs normally (but slowly).
Welcome to the forum @alexandre.durand. Cached particles may have been corrupted. Can you re-try the SSD-enabled job after deleting the cryoSPARC cache’s content?
@alexandre.durand A possible next step is to compare (for a job that has failed in this manner), the particle files’ checksums between the “persistent” and the cached copies.
If there’s any suspicion that the device hosting the cache is failing, one could run tests provided by smartmontools or nvme-cli packages, depending on the type of the cache device.