You might face a problem similar to Change cryosparc hostname - #11 by BrianCuttler.
… increases the risk that the CryoSPARC instance can be operated by the incorrect Linux user. What prompted the inclusion of CRYOSPARC_FORCE_USER in the configuration?
What are the output of the commands
ls -l /biotools8/biotools/cryosparc/cryosparc_master/run
ls -al /biotools8/biotools/cryosparc/cryosparc_master/run/