Thanks for the post! In CryoSPARC v4.1 (released December 12, 2022), we’re excited to announce a new Python library, cryosparc-tools, that allows you perform tasks like this much easier: Getting Started — cryosparc-tools
We have an example of how to generate high-resolution 2D class images. Producing images of particle stacks should be similar.
- Suhail