Structura Biotechnology(CryoSparc) representation at meetings (in-person)

Hi @Mark-A-Nakasone

Thank you. I’m familiar with the EMPIAR entry. I had reprocessed it when it was first released.

From the poster, I got the impression that the team had applied 3D-Flex refinement to it, which could have addressed relative flexibility in the receptor’s ectodomain. I’m curious about the job parameters and, in particular, treatment of the micelle–if at all–during mesh generation.

@apunjani had outlined a few general ways of prosecuting the segmentation of the sub-regions in a previous thread. Wondering if the team found one strategy more amenable than the others in the case of CGRPR.

Cheers,
Yang

1 Like