Hi, to use cryoPROS, I need mrcs.particels.
to make particles in one file, I used particle-stack job, which produced a mrc.particles file containing all particles I need. I wonder if there’s anything difference between mrc. and mrcs. . If there’s some differences, is there anyway to make parciles I need in cryosparc to become one mrcs.file?
thanks a lot~!
.mrc and .mrcs are the same - it is only the filename that differs, which you can change if needed.
As Oli says, they’re the same. Just symlink all the .mrc files to .mrcs if you don’t want to risk upsetting CryoSPARC. 
“Just symlink all the .mrc files to .mrcs”
sorry, I haven’t done anything like that.
may you tell more about it, or if there’s any detailed articles I can refer to？
thanks a lot
I would recommend spending a little time learning basic file handling in the Linux terminal (bash is the now the most commonly used one) and the various system utility programs.
However, if you’re still struggling, navigate to the directory where the stacks are in your CryoSPARC project directory, and something like:
for f in *mrc; do ln -s "$f" "$(basename "$f" .mrc)".mrcs; done
will symlink all *.mrc files to *.mrcs of the same basename, while leaving other files alone. I did test the above command, but as I say above, it’s better to understand what you’re doing before just blindly running commands off the internet.
Thanks a looooot 