Request for Topaz general picking and denoising to be added to CryoSPARC Live


Can the Topaz pre-trained picking models and pre-trained denoising models be added to the CryoSPARC Live workflow to allow for potentially better picking and visualization on the fly?

Thank you,


This would be a great feature for us as well.

Seconded! Have some datasets where blob/template picking is rather useless and already have a good Topaz model trained

100% this would be great to have!

On the fly denoising would be great so long as the automatic contrast adjustment is fixed!

Currently Topaz denoise works great but visualization of the resulting denoised micrographs within cryosparc leaves a lot to be desired: (Manual picker clips highlights of denoised micrographs - #2 by olibclarke)