Merging two datasets having different pixels

Hello,
I wish to merge two datasets with different pixel sizes. So, there are mainly two ways of doing so-

  1. Merge the micrographs
  2. Merge the particles
    I need to merge the micrographs, so what can be done?
    Also, how to cross-check whether the pixel size has changed or not?

I know this topic has been discussed previously, but I am confused about the F-crop calculation.
Thank you.

Hello sky,
I happend to see this paper related with data merge:

hope it helps.
best luck
Ge