Mask for heterogeneous refinement

Would be great to be able to use a mask in heterogeneous refinement. With small membrane proteins, we do this often and it would be nice to be able to do everything inside cryosparc without having to export to relion.

Thanks!

6 Likes

100% agreed, especially with the ability to restrict or eliminate alignment. Heterogeneous local refinement with non uniform regularization would be the dream I think…

3 Likes

Hi, I also want to use a mask in the heterogeneous refine. Will this function be available soon?
Thank you!