Hi,
I wonder if it is possible to replace particles (obtained from patch motion) from a local refinement job with the equivalent particles after a Reference motion correction. It is perhaps best illustrated in this example:
In my dataset, I used cryoSPARC live pre-processing, and then started several classification and local refinement jobs with particles obtained from the patch motion corrected micrographs. In parallel, I ran reference based motion correction which took several days but improved the resolution from 2.75 to 2.5Å. I would now like to combine the two processing paths: Maintain the poses and the particle subset identified in my classification and local refinement jobs, but use the extracted particles from the reference based motion correction job. Hopefullt with another round of local refinement and local searches this would improve the resolution of the local refinements.
While I can probably stitch something together using conversion to star files and some awkward bash scripts, I wondered if there is a more elegant solution to the problem directly within cryosparc.
Many thanks,
Matthias