Ewald sphere correction - homogenious vs non-uniform refinement

[Dmitry]

Hello,

Could anyone explain why the Ewald sphere correction option may not be present in 3D non-uniform refinement alignment?

According to the tutorial [Tutorial: Ewald Sphere Correction - CryoSPARC Guide](https://tutorial Ewald sphere ), after defining the sign of the Ewald sphere, one can repeat the Homogeneous refinement with the correct Ewalp sphere specification. So why not non-uniform refinement then?

Thank you

Sincerely,
Dmitry

[user123]

Ewald sphere correction not usable

Hi @tarek, Apologies for this – Ewald sphere correction was only formally added to the Homogeneous reconstruction, homogeneous refinement, and CTF refinement jobs (it was a bug that these parameters appear on the non-uniform refinement job, which we will resolve in a patch). Of course, you may still want to use the two in conjunction. Right now the best way to do that is to run non-uniform refinement without EWS enabled, and then use the output particles (and output FSC mask) as the inputs to …

[mmclean]

Hi @Dmitry,

Thanks for raising this; adding Ewald sphere correction to non-uniform refinement is now on our to-do list!

Best,
Michael