Hi @holmeschiu,
We’ve recently seen this error come up here: Error during refinement with C4 symmetry
We’re still not entirely sure about what may be causing this- although after a little digging online, some people have said that completely reinstalling any NVIDIA drivers/ CUDA packages helped them. Is it possible for you to try to install the latest version of CUDA, and then recompile pycuda? You can do this by following this post: Cryosparc v2.4.6 w/cuda 10?
If you are not able to install a new version of CUDA or reinstall your current version of CUDA, you can try reinstalling cryoSPARC: https://cryosparc.com/docs/reference/install/#forced-update