Hi @marinegor ,
Thanks for the post. Could you please take a look at this Apache configuration another user posted? We’ve tested and confirm it works as expected: CryoSparc 4.0.1 doesn't work behind reverse proxy? - #2 by clil16
For reference, if you hosted CryoSPARC via NGINX there shouldn’t be any configuration changes required from v3 to v4.
- Suhail