Add symmetry expansion option to local refinement? [Feature request]

request_recorded

#1

Hi,

Please add an option to use or create a symmetry expanded set of particles to the local refinement job - without this it is unfortunately only useful for asymmetric particles. I tried importing a symmetry-expanded set of particles created in relion from cryosparc output, but cryosparc cannot recognize the orientation information and throws an error.

Cheers
Oli


#2

Alternatively, would it be possible for cryosparc to retain orientation information when importing from a star file?


#3

Hi @olibclarke,

We are working on a major new pipeline for general multi-part refinements that will cover symmetry expansion as a special case. For now though we will add pose import for .star files!

Ali


#4

That would be fantastic, thank you @apunjani!! Would love to be able to try local refinement! :slight_smile: