Dear cryosparc developers,
I have recently encountered a problem in data processing of an ET data set. The target protein complex exhibits considerable conformational flexibility. I’m wondering if the adaptive regularization job could be provided as a separate job type (non-uniform refinement without alignment) so that half-maps derived from other software or datatypes could be imported into cryosparc for better resolution and interpretation?
Thanks in advance!
Best,
Gaoxing