You may have installed a newer version of Topaz that we have not tested within CryoSPARC.
I tested within CryoSPARC a Topaz v0.2.5 installation. For this purpose, I modified the instructions at the Topaz repository to force installation of specific versions for Topaz and the mkl dependency.
conda create -n topaz-0.2.5-20241217 python=3.6
conda activate topaz-0.2.5-20241217
conda install topaz=0.2.5 pytorch=1.10.2=py3.6_cuda11.3_cudnn8.2.0_0 mkl=2024.0.0 -c tbepler -c pytorch
I ensured that the conda environment was stored on a share that was accessible to the CryoSPARC worker and defined Path to Topaz executable as
/path/to/envs/topaz-0.2.5-20241217/bin/topaz