Thanks for posting these outputs.
The symptoms do not exactly match a problem that should be fixed by either a patch for v4.5.3 or, following @Mark-A-Nakasone’s suggestion, an update to v4.6.0, but you may want to try patching or updating anyway.
Given the port number outside the port range of the CryoSPARC master processes shown in your log and ps outputs, does your browser run on a computer other than the CryoSPARC master, and you forwarded a port from the “browser computer” with an ssh command like
ssh -L 16711:[...]
?