CryoSPARC officially does support CentOS 7, however it’s not a OS that we generally recommend due to some stability issues we’ve seen related to the older kernel version, older system library versions and GPU/Driver/CUDA compatibility. That said, we have addressed most of these issues in the latest versions of cryoSPARC and future versions should be relatively stable.
If you have a hard time getting a workstation running an OS other than CentOS 7 you can still very much use CryoSPARC. Otherwise we recommend an Ubuntu LTS installation.