Hi @leobets,
Thanks for the request. Are you attempting to flip the hand of each volume from the output of a homogeneous/non-uniform/local refinement / 3D classification, or are you instead flipping the hand of a 3D Flex model output from 3D Flex Reconstruct (inferred from this post)?
If it’s the former, you may be able to accomplish this via the “Flip the reconstruction hand” in Homogeneous Reconstruction Only, which will take particles re-reconstruct the volume with the particles’ alignments transformed to correct for the hand-flip.
If it’s the latter, unfortunately you’re right that this has to be done manually via Volume Tools for each volume. If this is a step you have to do frequently, and if you’re open to some scripting via CryoSPARC Tools, it would be possible to do so by programmatically creating Volume Tools jobs and then connecting each of the map inputs.
Best,
Michael