Thank you for your suggestion.
Here is my system information:
box size: 448
Eventlog：Non-uniform regularization with compute option: GPU
Running local cross validation for A …
====== Job process terminated abnormally.
Metadatalog: main process now complete at 2026-04-17 11:27:20.644164
monitor process now complete at 2026-04-17 11:27:21.203514
RAM:total 31Gi
Additionally, my samples consist of rod-like proteins like microtubules, with flexible proteins attached to their outer surfaces. Therefore, I’m using a box size of 448. Will enabling the “Non-uniform refine” option have any significant impact on my results?